Abnormal behavior induced by intracerebroventricular injection of thyrotropin releasing hormone (TRH) in rats

Effect of cholecystokinin on thyrotropin releasing hormone (TRH)-induced serotonin potentiation in rats.

Cholecystokinin octapeptide (CCK-8) did not affect the behavioral syndrome of rats treated with pargyline and 5-hydroxytryptamine, while TRH produced a marked behavioral excitation under the same condition. However, the serotonin-potentiating effect of TRH was apparently suppressed by simultaneous administration of CCK-8.

Thyrotropin-releasing hormone (TRH)-induced gastric acid secretion in aging rats.

Regulation by thyrotropin-releasing hormone (TRH) of TRH receptor mRNA degradation in rat pituitary GH3 cells.

In rat pituitary GH3 cells, thyrotropin-releasing hormone (TRH) down-regulates TRH receptor (TRH-R) mRNA (Fujimoto, J., Straub, R.E., and Gershengorn, M.C. (1991) Mol. Endocrinol. 5, 1527-1532), at least in part, by stimulating its degradation (Fujimoto, J., Narayanan, C.S., Benjamin, J.E., Heinflink, M., and Gershengorn, M.C. (1992) Endocrinology 130, 1879-1884). Here we show that TRH regulate...

Hyperthermia induced by thyrotropin-releasing hormone (TRH, protirelin) in the rat.

Recently, many literatures on neurohormones have been published. Among the peptides in the brain, thyrotropinreleasing hormone (TRH, protirelin) has been studied not only because of its usefulness for diagnostic and/or therapeutic aspects of neuroendocrinological disorders but also because of its eff icacies on some psychiatric disorders. Prange and Wilson (1972 a) and Prange et al. (1972b) rep...

The thyrotropin-releasing hormone (TRH)-immune system homeostatic hypothesis.

Decades of research have established that the biological functions of thyrotropin-releasing hormone (TRH) extend far beyond its role as a regulator of the hypothalamic-pituitary-thyroid axis. Gary et al. [Gary, K.A., Sevarino, K.A., Yarbrough, G.G., Prange, A.J. Jr., Winokur, A. (2003). The thyrotropin-releasing hormone (TRH) hypothesis of homeostatic regulation: implications for TRH-based ther...